The Importance of the Vervet (African Green Monkey) as a Biomedical Model
نویسنده
چکیده
The vervet monkey (Chlorocebus aethiops, formerly Cercopithecus aethiops) has long been among the most important non-human primate (NHP) models for biomedical research, with a PubMed citation record (over the past 10 years) close to that of rhesus macaque and much greater than that of any other NHP. The dramatic recent growth in the use of vervet as a model derives in part from its recognized utility as an old world monkey alternative to the rhesus macaque, of which there is now a critical shortage for biomedical research. In contrast, Caribbean-derived vervets are abundant, disease-free, small statured, and easy to handle. In addition, HIV research also has an increasing focus on vervets because in contrast to macaques, they are readily infected with simian immunodeficiency virus (SIV) but do not progress to disease.
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Yersinia enterocolitica Infection in a Vervet Monkey (Cercopithecus aethiops) in Iran
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